Natural Compound May Restore Memory Function in Alzheimer’s Patients
A new study finds that calcium alpha-ketoglutarate (CaAKG) may restore brain memory functions and protect neurons from early degeneration in Alzheimer’s disease.
Researchers at the National University of Singapore have discovered a natural compound, calcium alpha-ketoglutarate (CaAKG), capable of restoring key memory-related brain functions impaired by Alzheimer’s disease.
According to Medical Xpress, citing Aging Cell, CaAKG is a safe, naturally occurring metabolite commonly studied for healthy aging. The study shows it enhances synaptic plasticity, restores memory-related neural signaling, and protects neurons from early degenerative changes.
Professor Brian Kennedy, head of the Translational Research Program for Healthy Longevity, highlighted the promising potential of natural compounds to slow memory loss and support brain health with aging. CaAKG could complement existing therapies and offer a safe, widely accessible approach.
The research further indicates that CaAKG improves not only neural signaling but also associative memory and autophagy, the brain’s natural “cleanup” system that removes damaged proteins, supporting both basic memory and complex learning processes that decline early in Alzheimer’s disease.
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