In a remarkable scientific breakthrough, researchers at Osaka Metropolitan University have unveiled a new stem cell-based therapy capable of repairing spinal fractures caused by osteoporosis. The method uses stem cells extracted from body fat and has shown promising results in animal trials.

According to findings published in Bone & Joint Research, the technique involves turning adipose-derived stem cells (ADSCs) into three-dimensional bone-like spheroids that stimulate bone regeneration and healing. These cells are easy to obtain, even from elderly patients, and cause minimal strain on the body, making them a safe and practical alternative to surgery.

How the treatment works
The research team engineered bone spheroids from ADSCs and combined them with beta-tricalcium phosphate, a compound widely used in bone reconstruction. When implanted into mice with spinal fractures, the treatment significantly improved bone regeneration and strength, while activating genes linked to bone formation.

Scientists believe this discovery could revolutionize the treatment of osteoporotic vertebral fractures, one of the most common injuries among aging populations. Because the stem cells come from fat tissue, the procedure is less invasive and reduces patient risk compared to traditional methods.

The study opens the door to future non-surgical treatments for complex fractures, potentially accelerating recovery and enhancing the quality of life for millions of osteoporosis patients.