Researchers Develop New Treatment for Aggressive Triple-Negative Breast Cancer

A team of US scientists has developed a new molecule to treat triple-negative breast cancer, an aggressive type currently lacking effective therapies.

  Sat , November 08 2025 / 04:56 PM Updated At: 2025-11-08 16:56:38

علاج جديد لسرطان الثدي الثلاثي السلبي

Researchers at Oregon Health & Science University developed a new molecule called SU212 to target resistant cases of triple-negative breast cancer, which accounts for about 15% of all breast cancers.

How SU212 Works
In mouse models, SU212 binds to the enzyme Enolase 1 (ENO1), which regulates glucose levels in cells and is overexpressed in cancerous cells. The molecule triggers the enzyme's breakdown, suppressing tumor growth and spread, offering promising new avenues for treating this aggressive cancer type.

Future Applications
SU212 may also benefit other cancers involving ENO1, such as glioblastoma, pancreatic cancer, and thyroid cancer. The next step is advancing the molecule to clinical trials in humans after obtaining necessary approvals.

Importance of Early Detection
Early detection remains key to successful treatment. Recommended screenings include:

  • Self-examination: Monthly checks for changes in breast shape or texture.

  • Clinical exams: Performed by a doctor to detect abnormalities.

  • Imaging tests: Mammograms or ultrasounds based on risk factors and medical advice.

Any change in breast size or shape, persistent pain, redness, or a lump should prompt immediate medical consultation.

Apr 23
أهم الفحوصات الدورية لكل سن

Regular health screening is one of the most important steps to maintain good health and detect diseases early. The essential medical checkups for every age help in preventing complications and ensuring a healthier life.

Apr 23
ازاي تقرأ نتائج التحاليل بشكل صحيح

Many people, after doing medical tests, receive their results and immediately start looking at numbers and unfamiliar terms like (High – Low – Normal) without fully understanding what they actually mean.

Apr 23
دليل مبسط لفهم الدرجات الطبية

When dealing with medical services, many people come across different titles for doctors such as “Specialist” and “Consultant”, which can sometimes create confusion about what each title actually means and how they differ from each other.

Apr 23
دليل مبسط لفهم متى تحتاج استشارة طبية

Choosing the right time to visit a doctor is not a random decision. It can directly affect how quickly a condition is diagnosed and how effective the treatment will be. Many people delay visiting a doctor or go at the wrong time, which may lead to worsening symptoms or delayed care.